Scientific Studies: Polyrhachis Ant Extract

Several scientific studies of ethanol extract of Chinese Medicinal Ants, genus Polyrhachis, have produced data supporting its beneficial pharmacologic effects. Animal studies under laboratory conditions as well as human trials in a clinical setting present strong evidence of anti-inflammatory and analgesic properties, remarkable anti-oxidant activity, and direct curative effect on rheumatoid arthritis and chronic hepatitis. Evidence also suggests the Extract may support the treatment of related diseases like lupus and fibromyalgia, and conditions characterized by severe inflammation such as ankylosing spondylitis.

German Paper on Synthesis of Polyrhacitides A and B

The Chemical Ingredients, Pharmacological Effects and Clinical Applications of Chinese Ant Extract Preparations

Analgesic and Anti-inflammatory Activity of Polyrhachis

 

Total Synthesis of Polyrhacitides A and B by use of an Iterative Strategy for the Stereoselective Synthesis of 1,3-Polyol Arrays

Helge Menz and Stefan F. Kirsch, Department Chemic and Catalysis Research Center, Technische Universitat Munchen, Germany, September 16, 2009.

Polyrhacitide A and Polyrhacitide B moleculesIn late 2009 a German team at the University of Munich, funded by German pharmaceutical giant Boehringer Ingleheim, studied two newly isolated natural molecules, Polyrhacitide A and Polyrhacitide B, discovered in 2008 by a Chinese research team, and found in the Chinese Medicinal Ant, genus Polyrhachis.

They detail in the paper how they achieved the artificial production of these natural molecules in the laboratory for the purposes of developing proprietary pharmaceuticals based on the effectiveness of Chinese Medicinal Ant Extract.

View our complete summary of this paper here.

 

The Chemical Ingredients, Pharmacological Effects and Clinical Applications of Chinese Ant Extract Preparations

Yi Zhao, Miao Liu, Yuxiang Ma, Xiaoyan Wang, Shigeru Okada and Akitane Mori, published in: Institute of Traditional Chinese Medicine, Guanxi College of TCM, Nanning, China; Chinese National Department of Public Health, Department of Pathology; and Institute of Molecular and Cellular Medicine, Okayama University Medical School, Okayama, Japan, 2001.

This comprehensive paper by Dr. Yi Zhao summarizes the results of many earlier studies of the chemical composition, pharmacological effects and non-toxicity of Chinese Medicinal Ant Extract. These studies show strong evidence of anti-inflammatory and anti-oxidant effects, with some suggestion of immune-boosting and positive effects on sexual function. Dr. Zhao is the leading authority on Extract of Polyrhachis vicina Roger and has extensively studied the Extract for over 20 years. This paper was published by his home University and Hospital in Nanning, China, in the Chinese National Department of Health, and in Okayama University in Japan when he was visiting professor there.

View our complete summary of this paper here.

 

Analgesic and Anti-inflammatory Activities of Total Extract and Individual Reactions of Chinese Medicinal Ants Polyrhachis Lemellidens

Junping Kou, Yun Ni, Na Li, Jinrong Wang, Liang Liu and Zhi-Hing Jiang, published in The Biological and Pharmaceutical Bulletin of the Pharmaceutical Society of Japan, 2005.

Polyrhachis exhibits anti-inflammatory effects in animal studiesThe ethanol extract of Chinese medicinal ants Polyrhachis lamellidens was evaluated for its analgesic and anti-inflammatory activities in mice. It was shown that the extract significantly inhibited acetic acid-induced writhing response and increased hot-plate pain threshold of mice. Such action was similar to that of the ethanol extract of Polyrhachis vicina Roger, which also showed significant analgesic effect. Polyrhachis extract also significantly inhibited the increase in vascular permeability in acetic acid-induced peritoneal cavity irritation and in xylene-induced ear edema in mice, both typical tests for anti-inflammatory activity. These results suggest that P. lamellidens presents remarkable analgesic and anti-inflammatory activity, which supports the traditional use of medicinal ants of genus Polyrhachis in the treatment of various diseases associated with inflammation, including rheumatoid arthritis and chronic hepatitis.

View our complete summary of this paper here.